12/31/2023 0 Comments Difusion zfuseZFUZE outperformed Nano-surfaced Titanium and conventional PEEK on a statistically significant basis across all three studies. A series of N-powered cellular assays were studied, which compared Macrophage Polarization, Osteoblast Growth, and Bone Morphogenic Protein Upregulation. These foreign body responses lead to long-term chronic inflammation and a multitude of patient complications.nnThe Osteoimmunology research was conducted at the McGowan Institute for Regenerative Medicine at the University of Pittsburgh by Stephen Badylak, MD, DVM, PhD. ZFUZE is the first biomaterial specifically engineered to interact with the human immune system such that the human immune system does not attack it as a foreign body. Just in case you missed the "mic drop" at North American Spine Society (NASS) a couple of weeks back:n"AUSTIN, Texas-(BUSINESS WIRE)-DiFusion Inc, unveiled groundbreaking Osteoimmunology data at the North American Spine Society 2020 Annual Meeting demonstrating the superiority of the new biomaterial ZFUZE over Nano-Surfaced Titanium and conventional PEEK materials. Research presented at the 2019 NASS annual meeting suggests that the material discourages the fibrous encapsulation typical of standard PEEK and encourages a favorable shift in the phenotype of macrophages to an anti-inflammatory state."nnRead the full article from #MarketScope here:nn Initial research shows greater ongrowth and ingrowth of bone. The material is made of PEEK and zeolite, an aluminosilicate mineral that is negatively charged and hydrophilic. The Xiphos interbody device was cleared for use in the US in November 2019. 12 article:nn"The most recent PEEK composite to reach the market is Zfuse from DiFusion Technologies. This is groundbreaking, and we can't wait to bring the device industry even more data and ground-breaking results as we round the corner to 2021 and beyond.nnFrom the Feb. nnIt's great to see what was being said back then and compare it to how far we've come with research and the amazing case results in such a short time. 12, 2020 to be exact.back when we were just starting to make some noise with ZFUZE™. Throwback Thursday to waaaay back when.Feb.
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